Search results for "Chromosomal translocations"

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Convergent adaptation of Saccharomyces uvarum to sulfite, an antimicrobial preservative widely used in human-driven fermentations

2021

Different species can find convergent solutions to adapt their genome to the same evolutionary constraints, although functional convergence promoted by chromosomal rearrangements in different species has not previously been found. In this work, we discovered that two domesticated yeast species, Saccharomyces cerevisiae, and Saccharomyces uvarum, acquired chromosomal rearrangements to convergently adapt to the presence of sulfite in fermentation environments. We found two new heterologous chromosomal translocations in fermentative strains of S. uvarum at the SSU1 locus, involved in sulfite resistance, an antimicrobial additive widely used in food production. These are convergent events that …

Metabolic ProcessesCancer ResearchAdaptation BiologicalYeast and Fungal ModelsArtificial Gene Amplification and ExtensionWineChromosomal translocationQH426-470BiochemistryGenomeTranslocation Geneticchemistry.chemical_compoundAnti-Infective AgentsMedicine and Health SciencesPromoter Regions GeneticPhylogenyGenetics (clinical)GeneticsChromosome BiologyAlcoholic BeveragesEukaryotaGenomicsChromosomal AberrationsPolymerase chain reactionChemistryExperimental Organism SystemsPhysical SciencesChromosomes FungalResearch ArticleSaccharomyces cerevisiae ProteinsAnion Transport ProteinsSaccharomyces cerevisiaeLocus (genetics)Saccharomyces cerevisiaeChromosomal translocationsBiologyResearch and Analysis MethodsBeveragesSaccharomycesModel OrganismsSulfiteGeneticsHumansSulfitesMolecular Biology TechniquesMolecular BiologyGeneEcology Evolution Behavior and SystematicsNutritionChemical CompoundsOrganismsFungiBiology and Life SciencesCell Biologybiology.organism_classificationYeastYeastDietMetabolismchemistryFermentationFood PreservativesAnimal StudiesAdaptationPLOS Genetics
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